
张艳,博士、副教授
江苏徐州人,2011年博士毕业于南京大学化学化工学院有机化学专业。在Nature Communications、Journal of the American Chemical Society、ACS Catalysis、Water Research等期刊以第一作者或通讯作者发表SCI论文30余篇。
研究领域:
化学-酶催化合成药物及中间体
论文成果:
1. Kai Fu, et al, Yan Zhang*, Yijian Rao*. Unlocking enzymatic deracemization of structurally diverse allenes by designed photoenzymes. Nat Commun. 2026, 17: 2082.
2. Changtong Zhu#, Yan Zhang#, et al, Zhenbo Yuan*. Photoenzymatic catalysis enables enantioselective radical dearomative spirocyclization. Nat Commun. 2026, 17: 1272.
3. Min Li#, Yan Zhang#, et al, Yijian Rao*. Light-driven deracemization by a designed photoenzyme. J Am Chem Soc. 2025, 147: 13190-13199.
4. Honghui Zhang#, Yan Zhang#, et al, Yijian Rao*. Modular chemoenzymatic cascade for highly diastereo-and enantioselective synthesis of 1,3-disubstituted tetrahydroisoquinolines. ACS Catal. 2025, 15: 5426-5434.
5. Lifeng Yang, et al, Yan Zhang*. Highly efficient biosynthesis of rebaudioside M8 through structure-guided engineering of glycosyltransferase UGT94E13. J Agric Food Chem. 2024, 72: 15823.
6. Lifeng Yang, et al, Jinsong Shi*, Yan Zhang*. Selective synthesis of rebaudioside M2 through structure-guided engineering of glycosyltransferase UGT94D1. Front Bioeng Biotechnol. 2024, 12: 1334427.
7. Lifeng Yang, et al, Jinsong Shi*, Yan Zhang*. Selective biosynthesis and evaluation of rebaudioside M8 with improved organoleptic property and significant inhibition on inflammatory factor TNF-α. Food Biosci, 2024, 59: 103898.
8. Meiling Liu#, Yan Zhang#, et al, Yijian Rao*. Cercosporin-bioinspired photoinactivation of harmful cyanobacteria under natural sunlight via bifunctional mechanisms. Water Res. 2022, 215: 118242.
9. Min Li#, et al, Yan Zhang*, Yijian Rao*. Discovery and characterization of a novel perylenephotoreductant for the activation of aryl halides. J Catal. 2021, 399: 111.
10. Yan Zhang, et al, Yijian Rao*. Energy-transfer-mediated photocatalysis by a bioinspired organic perylenephotosensitizer HiBRCP. J Org Chem. 2021, 86: 15284.