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张艳

2026年03月30日 21:04 fmme 点击:[]

张艳,博士副教授

江苏徐州人,2011年博士毕业于南京大学化学化工学院有机化学专业。在Nature Communications、Journal of the American Chemical Society、ACS Catalysis、Water Research等期刊以第一作者或通讯作者发表SCI论文30余篇。


研究领域:

化学-酶催化合成药物及中间体

论文成果:

1. Kai Fu, et al, Yan Zhang*, Yijian Rao*. Unlocking enzymatic deracemization of structurally diverse allenes by designed photoenzymes. Nat Commun. 2026, 17: 2082.

2. Changtong Zhu#, Yan Zhang#, et al, Zhenbo Yuan*. Photoenzymatic catalysis enables enantioselective radical dearomative spirocyclization. Nat Commun. 2026, 17: 1272.

3. Min Li#, Yan Zhang#, et al, Yijian Rao*. Light-driven deracemization by a designed photoenzyme. J Am Chem Soc. 2025, 147: 13190-13199.

4. Honghui Zhang#, Yan Zhang#, et al, Yijian Rao*. Modular chemoenzymatic cascade for highly diastereo-and enantioselective synthesis of 1,3-disubstituted tetrahydroisoquinolines. ACS Catal. 2025, 15: 5426-5434.

5. Lifeng Yang, et al, Yan Zhang*. Highly efficient biosynthesis of rebaudioside M8 through structure-guided engineering of glycosyltransferase UGT94E13. J Agric Food Chem. 2024, 72: 15823.

6. Lifeng Yang, et al, Jinsong Shi*, Yan Zhang*. Selective synthesis of rebaudioside M2 through structure-guided engineering of glycosyltransferase UGT94D1. Front Bioeng Biotechnol. 2024, 12: 1334427.

7. Lifeng Yang, et al, Jinsong Shi*, Yan Zhang*. Selective biosynthesis and evaluation of rebaudioside M8 with improved organoleptic property and significant inhibition on inflammatory factor TNF-α. Food Biosci, 2024, 59: 103898.

8. Meiling Liu#, Yan Zhang#, et al, Yijian Rao*. Cercosporin-bioinspired photoinactivation of harmful cyanobacteria under natural sunlight via bifunctional mechanisms. Water Res. 2022, 215: 118242.

9. Min Li#, et al, Yan Zhang*, Yijian Rao*. Discovery and characterization of a novel perylenephotoreductant for the activation of aryl halides. J Catal. 2021, 399: 111.

10. Yan Zhang, et al, Yijian Rao*. Energy-transfer-mediated photocatalysis by a bioinspired organic perylenephotosensitizer HiBRCP. J Org Chem. 2021, 86: 15284.



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