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高聪

2025年09月14日 22:03 MMEC 点击:[]


高聪,副研究员、博士生导师


主要从事塑料单体与有机酸高效细胞工厂的构建与应用。已主持包括国家自然科学基金(面上和青年)、重点研发计划子课题、江苏省自然科学基金在内的国家或省部级课题6项。在Nat Commun, Metab Eng, 《生物工程学报》等学术期刊发表论文30余篇,申请或授权中国发明专利30余项。研究成果获江苏省科技进步一等奖、中国石油化工联合会科技进步一等奖和江苏省科学技术二等奖。


研究领域:

塑料单体与有机酸高效细胞工厂的构建与应用工作

论文成果:

1. Zhendong Li, et al, Cong Gao*, Liming Liu*. De novo designed protein guiding targeted protein degradation. Nature Communications, 2025, 16: 6598.

2. Cong Gao, et al, Liming Liu*. Programmable biomolecular switches for rewiring flux in Escherichia coli. Nature Communications, 2019, 10: 3751.

3. Shaolun Zhang, et al, Cong Gao*, Liming Liu*. Systems metabolic engineering of Klebsiella pneumoniae for high-level 1,3-propanediol production. Metabolic Engineering, 2026, 93: 1-13.

4. Zhendong Li, et al, Cong Gao*. Engineering metabolic flux for the microbial synthesis of aromatic compounds. Metabolic Engineering, 2025, 88: 94-112.

5. Cong Gao, et al, Liming Liu*. Dynamic consolidated bioprocessing for direct production of xylonate and shikimate from xylan by Escherichia coli. Metabolic Engineering, 2020, 60: 128-137.

6. Ruyin Chu, et al, Xiaomin Li*, Cong Gao*. Engineering a plasmid-free Escherichia coli for glutarate biosynthesis from glucose. Chemical Engineering Journal, 2025, 513: 163077.

7. Guangjie Liang, et al, Cong Gao*. Shortening electron transfer distance to enhance chemicals and electric energy production in Escherichia coli. Chemical Engineering Journal, 2024, 497: 154932.

8. Guangjie Liang, et al, Cong Gao*. Designing a periplasmic photosynthetic biohybrid system for succinate and electric energy production. Chemical Engineering Journal, 2023, 477: 147152.

9. Longfei Song, et al, Liming Liu*, Cong Gao*. Engineering Corynebacterium glutamicum for 1,5-pentanediamine production via enhanced product tolerance and efflux transport. Bioresource Technology, 2026, 447: 134178.

10. Kaifang Liu, et al, Cong Gao*. Microbial synthesis of glycosaminoglycans and their oligosaccharides. Trends in Microbiology, 2023, 31: 369-383.



联系电话:0510-85197357

联系邮箱:conggao@jiangnan.edu.cn






 
 




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