首页 研究中心成果 发表论文

203.Guangjie Liang(梁光杰), Cunping Liu, Jia Liu, Xuechen Xu, Jing Wu, Wei Song, Guipeng Hu, Wanqing Wei, Xiaomin Li, Jianxin Zhao, Liming Liu, Cong Gao*. Designing autonomous biological switches to rewire carbon flux for chemical production in Escherichia coli [J]. ACS Sustainable Chemistry & Engineering, 2024, accept.


202.Guangjie Liang(梁光杰), Yuan Liu, Ziyun Gu, Xiulai Chen, Wei Song, Wanqing Wei, Jing Wu, Guipeng Hu, Jianxin Zhao, Liming Liu, Cong Gao*. Shortening electron transfer distance to enhance chemicals and electric energy production in Escherichia coli[J]. Chemical Engineering Journal, 2024, 497: 154932.


201.Shuo Hou(侯烁), Cong Gao, Jia Liu, Xiulai Chen, Wanqing Wei, Wei Song, Guipeng Hu, Xiaomin Li, Jing Wu, Liming Liu*. Med3-mediated NADPH Generation to Help Saccharomyces cerevisiae Tolerate Hyperosmotic Stress[J]. Applied and Environmental Microbiology, 2024, 90(8):e0096824.


200.Chenghu Chen(陈城虎), Cong Gao, Guipeng Hu, Wanqing Wei, Xiaoge Wang, Jian Wen, Xiulai Chen, Liming Liu, Wei Song, Jing Wu*. Rational and semi-rational approaches for engineering salicylate production in Escherichia coli[J]. ACS Synthetic Biology, 2024, Accepted.    

    

199.Lei Wang(王蕾), Yaoyun Wu, Jun Hu, Dejing Yin, Wanqing Wei, Jian Wen, Xiulai Chen, Cong Gao, Yiwen Zhou, Jia Liu, Guipeng Hu, Xiaomin Li, Jing Wu, Zhi Zhou, Liming Liu & Wei Song*. Unlocking the function promiscuity of old yellow enzyme to catalyze asymmetric Morita-Baylis-Hillman reaction[J]. Nature Communications. 2024, 15(1):5737.    


198.Quan Liu(刘泉), Xiulai Chen, Guipeng Hu, Ruyin Chu, Jia Liu, Xiaomin Li, Cong Gao, Liming Liu, Wanqing Wei, Wei Song, Jing Wu*. Systems metabolic engineering of Escherichia coli for high-yield production of para-hydroxybenzoic acid. Food Chemistry, 2024, 457:140165.


197.Tianfu Wu(吴天福), Yihan Chen, Wanqing Wei, Wei Song, Jing Wu, Jian Wen, Guipeng Hu, Xiaomin Li, Cong Gao, Xiulai Chen, Liming Liu*. Mechanism-guided computational design drive meso-diaminopimelate dehydrogenase to efficient synthesis of aromatic D-amino acids. ACS Synthetic Biology, 2024, 13, 6, 1879–1892.


196.Chenni Zheng(郑晨妮), Wanqing Wei, Jian Wen, Wei Song, Jing Wu, Ran Wang, Dejing Yin, Xiulai Chen, Cong Gao, Jia Liu, Liming Liu*. Rational Design of the Spatial Effect in a Fe(II)/α-Ketoglutarate-Dependent Dioxygenase Reverses the Regioselectivity of C(sp3)-H Bond Hydroxylation in Aliphatic Amino Acids[J]. Angew. Chem. Int. Ed., 2024, 63, e202406060.


195.KOMERA Irene, Xiulai Chen, Liming Liu, Cong Gao*. Microbial synthetic epigenetic tools design and applications[Review]. ACS Synthetic Biology, 2024, 13(6):1621-1632.


194.Cunping Liu(刘存萍), Cong Gao, Longfei Song, Xiaomin Li, Xiulai Chen, Jing Wu, Wei Song, Wanqing Wei, Liming Liu*. Fine-tuning pyridoxal 5′-phosphate synthesis in Escherichia coli for cadaverine production in minimal culture media[J]. ACS Synthetic Biology, 2024, 13(6):1820-1830.


193.Dingyu Guo(郭丁钰), Zhengchao Wang, Wanqing Wei, Wei Song, Jing Wu, Jian Wen, Guipeng Hu, Xiaomin Li, Cong Gao, Xiulai Chen, and Liming Liu*. Rational design improves both thermostability and activity of a new D-tagatose 3-epimerase from Kroppenstedtia eburnean to produce D-allulose[J]. Enzyme and Microbial Technology, 2024, 178, 110448.


192.Ni Ping(倪平), Cong Gao, Jing Wu, Wei Song, Xiaomin Li, Wanqing Wei, Xiulai Chen, Liming Liu*. Production of 1,4-butanediol from Succinic acid using Escherichia coli Whole-cell Catalysis[J]. Chembiochem, 2024, 25(11):e202400142.


191.Chong Qiu(仇崇), Xiaoge Wang, Jiaojiao Zuo, Runyang Li, Cong Gao, Xiulai Chen, Jia Liu, Wanqing Wei, Jing Wu, Guipeng Hu, Wei Song, Nan Xu*, Liming Liu**. Systems engineering Escherichia coli for efficient production p-coumaric acid from glucose[J]. Biotechnology and Bioengineering, 2024, 121(7):2147-2162.


190.Xin Zhen(甄馨), XiSong Feng, Wei Song, Wanqing Wei, Jing Wu, Jian Wen, Guipeng Hu, Xiaomin Li, Cong Gao, Xiulai Chen, Liming Liu*. Engineering Tauriopine Dehydrogenase for Efficient Catalytic Synthesis of (R)-Alpha-ethyl-2-oxo-1-pyrrolidineacetic Acid[J]. Chemcatchem, 2024,16(16):e202400276.


189.Jing Wang(王晶), Xin Xu, Wanqing Wei, Wei Song, Jian Wen, Guipeng Hu, Xiaomin Li, Cong Gao, Xiulai Chen, Liming Liu, Jing Wu*. Rational design of Salmonella typhi acid phosphatase for efficient production of pyridoxal 5’-phosphate[J]. Journal of Agricultural and Food Chemistry, 2024, 72, 16, 9279–9288.


188.Ming Wang(王明), Haomiao Wang, Cong Gao, Wanqing Wei, Jia Liu, Xiulai Chen, Guipeng Hu, Wei Song, Jing Wu, Fan Zhang, Liming Liu*Efficient production of protocatechuic acid using systems engineering of Escherichia coli[J]. Metabolic Engineering, 2024, 82: 134-146.


187.Qi Sheng(盛琦), Lingxin Yi , Bin Zhong, Xiaoyu Wu, Liming Liu**, Bin Zhang*. Shikimic acid biosynthesis in microorganisms: Current status and future direction[J]. Biotechnology Advances, 2023, 62: 108073.


186.Tianfu Wu(吴天福), Wanqing Wei, Changzheng Gao, Jing Wu, Cong Gao, Xiulai Chen, Liming Liu, and Wei Song*. Synthesis of C-N bonds by nicotinamide-dependent oxidoreductase: an overview[J].Critical Reviews in Biotechnology, 2023, 1–25.


185.Yaoyun Wu (武耀运), Yaozhong Cui, Wei Song, Wanqing Wei, Zhizhen He, Jinyang Tao, Dejing Yin, Xiulai Chen, Cong Gao, Jia Liu, Liming Liu, Jing Wu*. Reprogramming the transition states to enhance C-N cleavage efficiency of Rhodococcus opacus L-amino acid oxidase[J]. JACS Au, 2024, 4: 557-569.


184.Kaifang Liu(刘开放), Xiulai Chen, Jing Wu, Wei Song, Wanqing Wei, Liming Liu, Cong Gao*. Multivariate modular metabolic engineering for high titer uridine triphosphate production in Escherichia coli[J]. ACS Sustainable Chemistry & Engineering2023, 12(1): 85-95.


183.Guangjie Liang(梁光杰), Xuechen Xu, Xiulai Chen, Jing Wu, Wei Song, Wanqing Wei, Jia Liu, Xiaomin Li, Liming Liu, Cong Gao*. Designing a periplasmic photosynthetic biohybrid system for succinate and electric energy production[J]. Chemical Engineering Journal, 2023, 477: 147152.


182.Irene Komera, Cong Gao, Xiulai Chen, Wei Chen, Liming Liu *. Synthetic epigenetics-assisted microbial chassis engineering[J]. Trends in Microbiology, 2023, 31(9): 889-893.


181.Ying Huang(黄盈),  Changzheng Gao, Wei Song, Wanqing Wei, Xiulai Chen, Cong Gao, Jia Liu, Jing Wu and Liming Liu*. Improving theaflavin-3,3′-digallate production efficiency optimization  by transition state conformation of polyphenol oxidase[J].  Molecules, 2023, 28(9): 3831.


180.Huanhuan Xu(徐欢欢), Bicheng Yu, Wanqing Wei, Xiulai Chen, Cong Gao, Jia Liu, Liang Guo, Wei Song, Liming Liu, and Jing Wu*. Improving tyrosol production efficiency through shortening the allosteric signal transmission distance of pyruvate decarboxylase[J]. Applied Microbiology and Biotechnology, 2023, 107(11): 3535-3549.


179.Landong Zhang(张岚东), Changzheng Gao, Wei Song, Wanqing Wei, Cong Gao, Xiulai Chen, Jia Liu, Liming Liu, and Jing Wu*. Improving D-carbamoylase thermostability through salt bridge engineering for efficient D-p-hydroxyphenylglycine production[J]. Systems Microbiology and Biomanufacturing, 2024, 4: 250-262.


178.Xin Li(李昕), Changzheng Gao, Wanqing Wei, Wei Song, Weiwei Meng, Jia Liu, Xiulai Chen, Cong Gao, Liang Guo, Liming Liu, and Jing Wu*. A tri-enzyme cascade for efficient production of L-2-aminobutyrate from L-threonine[J]. ChemBioChem, 2023, 24(15): e202300148.


177.Haoyu Liu(刘浩宇), Wanqing Wei, Zixuan Pang, Simin Gu, Wei Song, Cong Gao, Xiulai Chen, Jia Liu, Liang Guo, Jing Wu, Liming Liu*. Protein engineering, cofactor engineering and surface display engineering to achieve whole-cell catalytic production of chondroitin sulfate A[J]. Biotechnology and Bioengineering, 2023, 120(7): 1784-1796.


176.Jiahui Yang(杨家辉), Wanqing Wei, Changzheng Gao, Wei Song, Cong Gao, Xiulai Chen, Jia Liu, Liang Guo, Liming Liu, Jing Wu*.Efficient production of salvianic acid A from L-dihydroxyphenylalanine through a tri-enzyme cascade[J]. Bioresources and Bioprocessing, 2023, 10(1): 31.


175.Yang Tan(谭阳), Changzheng Gao, Wei Song, Wanqing Wei, Jia Liu, Cong Gao, Liang Guo, Xiulai Chen, Liming Liu, Jing Wu*. Rational design of meso-diaminopimelate dehydrogenase with enhanced reductive amination activity for efficient production of D-p-hydroxyphenylglycine[J]. Applied and Environmental Microbiology, 2023, 89(5): e00109-23.


174.Huiyun Zuo(左惠芸), Lihao Ji, Jingyu Pan, Xiulai Chen, Cong Gao, Jia Liu, Wanqing Wei, Jing Wu, Wei Song, Liming Liu*. Engineering growth phenotypes of Aspergillus oryzae for L-malate production[J]. Bioresources and Bioprocessing2023, 10(1): 25.


173.Xuling Jiang(姜旭玲), Wanqing Wei, Yaozhong Cui, Wei Song , Yingying Li, Xiulai Chen, Cong Gao, Jia Liu, Liang Guo, Liming Liu and Jing Wu *. A multi-enzyme cascade for efficient production of pyrrolidone from L-glutamate[J]. Applied and Environmental Microbiology, 2023, 89(4): e0001323.


172.Chenghu Chen(陈城虎), Xiulai Chen, Liming Liu, Jing Wu, Cong Gao*. Engineering Microorganisms to Produce Bio-Based Monomers: Progress and Challenges[J]. Fermentation, 2023, 9(2): 137.


171.Pei Zhou (周配), Hui Liu, Xin Meng, Huiyun Zuo, Mengya Qi, Liang Guo, Cong Gao, Wei Song, Jing Wu, Xiulai Chen, Wei Chen, Liming Liu*. Engineered artificial membraneless organelles in Saccharomyces cerevisiae to enhance chemical production[J]. Angewandte Chemie International Edition, 2023, 62(14): e202215778.


170.Yu Yan(燕宇), Chenni Zheng, Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Meng Zhu, Liming Liu*. Efficient Production of Epoxy‐Norbornane from Norbornene by an Engineered P450 Peroxygenase[J]. ChemBioChem, 2023, 24(3): e202200529.


169.Kaifang Liu(刘开放), Liang Guo, Xiulai Chen, Liming Liu, Cong Gao*. Microbial synthesis of glycosaminoglycans and their oligosaccharides[J]. Trends in Microbiology, 2023, 31(4): 369-383.


168.Zhendong Li(李振栋), Cong Gao, Chao Ye, Liang Guo, Jia Liu, Xiulai Chen, Wei Song, Jing Wu, Liming Liu*. Systems engineering of Escherichia coli for high-level shikimate production [J]. Metabolic Engineering, 2023, 75: 1-11.


167.Xiaobo Ruan(阮小波), Sheng Zhang, Wei Song, Jia Liu, Xiulai Chen, Liming Liu, Jing Wu*. Efficient synthesis of tyrosol from L-tyrosine via heterologous Ehrlich pathway in Escherichia coli[J]. Chinese Journal of Chemical Engineering, 2022, 47: 18-30.


166.Qiang Ding(丁强), Zhendong Li, Liang Guo, Wei Song, Jing Wu, Xiulai Chen, Liming Liu, Cong Gao*. Engineering Escherichia coli asymmetry distribution-based synthetic consortium for shikimate production[J]. Biotechnology and Bioengineering. 2022, 119(11): 3230-3240.


165.Yaqi Cheng(成雅琪), Wei Song, Xiulai Chen, Cong Gao, Jia Liu, Liang Guo, Meng Zhu, Liming Liu, Jing Wu*Efficient synthesis 1,4-cyclohexanedicarboxaldehyde by an engineered alcohol oxidase[J]. Bioresources and Bioprocessing, 2022, 9(1): 80.


volume

164.Dengke Gao(高登科), Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Liming Liu*. Efficient Production of L-homophenylalanine by  Enzymatic–Chemical Cascade Catalysis[J]. Angewandte Chemie International Edition, 2022, 61(36): e202207077.


163.Kuo Zhao(赵阔), Jianmin Liu, Cong Gao, Jia Liu, Xiulai Chen, Liming Liu, Liang Guo*. Advances in microbial production of feed amino acid[J]. Advances in Applied Microbiology, 2022, 119: 1-33.


162.Jie Liu(刘洁), Jianmin Liu, Liang Guo , Jia Liu, Xiulai Chen, Liming Liu, Cong Gao*. Advances in microbial synthesis of bioplastic monomers[J]. Advances in Applied Microbiology, 2022, 119: 35-81.


161.Yu Yan(燕宇), Jing Wu, Guipeng Hu, Cong Gao, Liang Guo, Xiulai Chen, Liming Liu, Wei Song*. Current state and future perspectives of cytochrome P450 enzymes for C-H and C=C oxygenation[J]. Synthetic and Systems Biotechnology, 2022, 7(3): 887-899.


160.Na Qi(齐娜), Jianmin Liu, Wei Song, Jia Liu, Cong Gao, Xiulai Chen, Liang Guo, Liming Liu, Jing Wu*. Rational design of phospholipase D to improve the transphosphatidylation activity for phosphatidylserine synthesis[J]. Journal of Agricultural and Food Chemistry, 2022, 70(22): 6709-6718.


159.Cong Gao(高聪), Liang Guo, Wei Song, Jing Wu, Xiulai Chen, Liming Liu*. Advances in microbial engineering for the production of value-added products in a biorefinery[J]. Systems Microbiology and Biomanufacturing, 2022: 633.


158.Zuwei Xu(徐祖伟), Lihao Ji, Wenxiu Tang, Liang Guo, Cong Gao, Xiulai Chen, Jia Liu, Guipeng Hu, Liming Liu*.Metabolic engineering of Streptomyces to enhance the synthesis of valuable natural products[J]. Engineering Microbiology, 2022, 2: 100022.


157.Yanli Qi(齐艳利), Nan Xu, Zehong Li, Jiaping Wang, Xin Meng, Cong Gao, Jian Chen, Wei Chen, Xiulai Chen, Liming Liu*. Mediator engineering of Saccharomyces cerevisiae to improve multidimensional stress tolerance[J]. Applied and Environmental Microbiology, 2022, 88: e01627-21.


156. Hui Liu(刘晖), Pei Zhou, Mengya Qi, Liang Guo, Cong Gao, Guipeng Hu, Wei Song, Jing Wu, Xiulai Chen, Jian Chen, Wei Chen, Liming Liu*. Enhancing biofuels production by engineering the actin cytoskeleton in Saccharomyces cerevisiae[J]. Nature Communications, 2022, 13: 1886.


155. Irene Komera, Cong Gao, Liang Guo, Guipeng Hu, Xiulai Chen, Liming Liu*.Bifunctional optogenetic switch for improving shikimic acid production in E. coli[J]. Biotechnology for Biofuels and Bioproducts, 2022, 15(1): 13.


154. Wei Song(宋伟), Kai Zheng, Xin Xu, Cong Gao, Liang Guo, Jia Liu, Xiulai Chen, Liming Liu, Guipeng Hu, and Jing Wu*Enzymatic production of ascorbic acid-2-Phosphate by engineered Pseudomonas aeruginosa acid phosphatase[J]. Journal of Agricultural and Food Chemistry2021, 69(47): 14215-14221. 


153. Qiang Ding(丁强), Yadi Liu; Guipeng Hu; Liang Guo; Cong Gao; Xiulai Chen; Wei Chen; Jian Chen; Liming Liu*Engineering Escherichia coli biofilm to increase contact surface for shikimate and L-malate production[J]. Bioresources and Bioprocessing2021, 8(1): 118.


152. Hui Liu (刘晖), Weijia Yuan, Pei Zhou, Guangjie Liang, Cong Gao, Liang Guo, Guipeng Hu, Wei Song, Jing Wu, Xiulai Chen, Liming Liu*. Engineering membrane asymmetry to increase medium-chain fatty acid tolerance in Saccharomyces cerevisiae[J]. Biotechnology and Bioengineering, 2021, 119(1): 277-286.


151.Wenwen Diao(刁文文), Liang Guo, Qiang Ding, Cong Gao, Guipeng Hu, Xiulai Chen, Yang Li, Linpei Zhang, Wei Chen, Jian Chen, Liming Liu*. Reprogramming microbial populations using a programmed lysis system to improve chemical production[J]. Nature Communications, 2021, 12(1): 6886.


150. Xin Xu (徐歆), Shengheng Yan, Xiaodong Hou, Wei Song, Lei Wang, Tianfu Wu, Mengya Qi, Jing Wu, Yijian Rao*, Binju Wang*, Liming Liu*. Local electric field modulated reactivity of Pseudomonas aeruginosa acid phosphatase for enhancing phosphorylation of L-ascorbic acid[J]. ACS Catalysis, 2021, 11(21): 13397-13407


149. Tian Tong(童天), Xiulai Chen, Guipeng Hu, Xiao-Ling Wang, Gao-Qiang Liu* and Liming Liu*. Engineering microbial metabolic energy homeostasis for improved bioproduction[J]. Biotechnology Advances, 2021, 53: 107841.


148. Cong Gao(高聪), Liang Guo, Guipeng Hu, Jia Liu, Xiulai Chen, Xiaoxia Xia, Liming Liu*. Engineering a CRISPRi circuit for autonomous control of metabolic flux in Escherichia coli[J]. ACS Synthetic Biology, 2021, 10(10): 2661-2671.


147. Yaoyun Wu(武耀运), Sheng Zhang, Wei Song, Jia Liu, Xiulai Chen, Guipeng Hu, Yiwen Zhou, Liming Liu, and Jing Wu*. Enhanced catalytic efficiency of L-amino acid deaminase achieved by a shorter hydride transfer distance[J]. ChemCatChem, 2021, 13(21): 4557-4566.


146. Kaifang Liu(刘开放), Xiulai Chen, Yunlu Zhong, Cong Gao, Guipeng Hu, Jia Liu, Liang Guo, Wei Song, Liming Liu*. Rational design of a highly efficient catalytic system for the production of PAPS from ATP and its application in the synthesis of chondroitin sulfate [J]. Biotechnology and Bioengineering, 2021, 118(11): 4503-4515.


145.Guangjie Liang (梁光杰), Pei Zhou, Jiaxin Lu, Hui Liu, Yanli Qi, Cong Gao, Liang Guo, Guipeng Hu, Xiulai Chen, Liming Liu*. Dynamic regulation of membrane integrity to enhance l‐malate stress tolerance in Candida glabrata [J]. Biotechnology and Bioengineering, 2021, 118(11): 4347-4359.


144. Tian Tong (童天), Zhenyan Tao, Xiulai Chen, Cong Gao, Hui Liu, Gao-Qiang Liu*, Liming Liu*. A biosynthesis pathway for 3-hydroxypropionic acid production in genetically engineered Saccharomyces cerevisiae[J]. Green Chemistry, 2021, 23(12): 4502-4509.


143. Cui Lu(卢翠), Sheng Zhang, Wei Song, Jia Liu, Xiulai Chen, Liming Liu, Jing Wu*. Efficient synthesis of D-phenylalanine from L-phenylalanine via a tri-enzymatic cascade pathway[J]. ChemCatChem, 2021, 13(13): 3165-3173.


142. Xu Tan (谭旭), Sheng Zhang, Wei Song, Jia Liu, Cong Gao, Xiulai Chen, Liming Liu, Jing Wu*. A multi-enzyme cascade for efficient production of D-p-hydroxyphenylglycine from l-tyrosine[J]. Bioresources and Bioprocessing, 2021, 8(1): 1-15.


141. Jiaping Wang(王镓萍), Cong Gao, Xiulai Chen, Liming Liu*. Engineering the Cad pathway in Escherichia coli to produce glutarate from L-lysine[J]. Applied Microbiology and Biotechnology, 2021, 105(9): 3587-3599.


140. Jiaping Wang(王镓萍), Cong Gao, Xiulai Chen, Liming Liu*. Expanding lysine industry: Biotechnological production of L-lysine and its derivatives[J]. Advances in Applied Microbiology, 2021, 115: 1-33.


139. Lei Wang (王蕾), Wei Song, Binju Wang, Yan Zhang, Xin Xu, Jing Wu, Cong Gao, Jia Liu, Xiulai Chen, Jinghua Chen, and Liming Liu*. One-pot enzymatic–chemical cascade route for synthesizing aromatic α-Hydroxy ketones[J]. ACS Catalysis,2021,11(5): 2808–2818.


138. Lihao Ji (季立豪), Ju Wang, Qiuling Luo, Qiang Ding, Wenxiu Tang, Xiulai Chen, Liming Liu*. Enhancing L-malate production of Aspergillus oryzae by nitrogen regulation strategy[J]. Applied Microbiology and Biotechnology, 2021, 105(8): 3101-3113.


137. Hui Liu (刘晖), Yanli Qi, Pei Zhou, Chao Ye, Cong Gao, Xiulai Chen, Liming Liu*. Microbial physiological engineering increases the efficiency of microbial cell factories[J]. Critical Review in Biotechnology, 2021, 41(3):339-354.


136.Xu Tan (谭旭), Wei Song, Xiulai Chen, Liming Liu, Jing Wu*Recent advances in biocatalytic derivatization of L-tyrosine[J]. Applied Microbiology and Biotechnology, 2020, 104(23): 9907-9920.


135. Qiang Ding (丁强), Wenwen Diao, Cong Gao, Xiulai Chen, Liming Liu*Microbial cell engineering to improve cellular synthetic capacity[J]. Biotechnology Advances, 2020, 40:107496.


134. Pei Zhou (周配), Xiaoke Yuan, Hui Liu, Yanli Qi, Xiulai Chen, Liming Liu*Candida glabrata Yap6 recruits Med2 to alter glycerophospholipid composition and develop acid pH stress resistance [J]. Applied and Environmental Microbiology, 2020, 24:e01915-20.


133. Wei Song (宋伟), Xin Xu, Cong Gao, Yuxuan Zhang, Jing Wu, Jia Liu, Xiulai Chen, Qiuling Luo, Liming Liu*. Open the gate of Corynebacterium glutamicum threonine deaminase for efficient synthesis of bulky α-keto acids[J]. ACS Catalysis, 2020, 10(17): 9994–10004.


132. Xiulai Chen (陈修来), Danlei Ma, Jia Liu, Qiuling Luo, Liming Liu*Engineering the transmission efficiency of the noncyclic glyoxylate pathway for fumarate production in Escherichia coli[J]. Biotechnology for Biofuels, 2020, 13(1):132.


131. Xiulai Chen (陈修来), Juyang Yi, Jia Liu, Qiuling Luo, Liming Liu*Enzymatic production oftrans-4-hydroxy-l-proline by proline 4-hydroxylase[J]. Microbial biotechnology, 2021, 14: 479-487.


130. Xiulai Chen (陈修来), Xiaoxiang Dong, Jia Liu, Qiuling Luo, Liming Liu*. Pathway engineering of Escherichia coli for α-ketoglutaric acid production[J]. Biotechnology and Bioengineering, 2020, 117: 2791-2801.


129. Jianshen Hou(侯建屾), Cong Gao(高聪), Liang Guo, Qiang Ding, Jens Nielsen, Wenxiu Tang, Guipeng Hu, Xiulai Chen, Liming Liu*. Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch [J]. Metabolic Engineering, 2020, 61: 47-57. (# Authors contributed equally)


128. Cong Gao (高聪), Liang Guo, Qiang Ding, Guipeng Hu, Chao Ye, Jia Liu, Xiulai Chen, Liming Liu*. Dynamic consolidated bioprocessing for direct production of xylonate and shikimate from xylan by Escherichia coli[J]. Metabolic Engineering, 2020, 60: 128-137.


127. Yuanyuan Qian (钱园园), Cui Lu, Jia Liu, Wei Song, Xiulai Chen, Qiuling Luo, Liming Liu, Jing Wu*Engineering protonation conformation of l-aspartate-α-decarboxylase to relieve mechanism-based inactivation[J]. Biotechnology and Bioengineering, 2020, 117: 1607-1614.

   

126. Xiulai Chen (陈修来), Juyang Yi, Wei Song, Jia Liu, Qiuling Luo, Liming Liu*Chassis engineering of Escherichia coli for trans-4-hydroxy-L-proline production[J]. Microbial Biotechnology, 2020, 14: 392-402.


125. Chao Ye (叶超), Nan Xu, Cong Gao, Gaoqiang Liu, Jianzhong Xu, Weiguo Zhang, Xiulai Chen, Jens Nielsen, Liming Liu*. Comprehensive understanding of Saccharomyces cerevisiae phenotypes with whole-cell model WM_S288C[J]. Biotechnology and Bioengineering, 2020, 117:1562-1574.


124. Guoxing Zhu (朱国星), Nannan Yin, Qiuling Luo, Jia Liu, Xiulai Chen, Liming Liu*, and Jianrong Wu. Enhancement of sphingolipids synthesis improves osmotic tolerance of Saccharomyces cerevisiae[J]. Applied and Environmental Microbiology, 2020, 8: e02911-19.


123. Liang Guo(郭亮), Wenwen Diao, Cong Gao, Guipeng Hu, Qiang Ding, Chao Ye, Xiulai Chen, Jia Liu, Liming Liu*. Engineering Escherichia coli lifespan for enhancing chemical production[J]. Nature Catalysis, 2020, 3:307-318.


122.Wei Song (宋伟), Xiulai Chen,  Jing Wu, Jianzhong Xu, Weiguo Zhang, Jia Liu, Jian Chen, Liming Liu*. Biocatalytic derivatization of proteinogenic amino acids for fine chemicals[J].  Biotechnology Advances, 2020, 40:107496.


121.Rui Yao (姚瑞), Pei Zhou, Chengjin Wu, Liming Liu*, Jing WuSml1 Inhibits the DNA Repair Activity of Rev1 in Saccharomyces cerevisiae during Oxidative Stress[J]. Applied and Environmental Microbiology, 2020, 84: e02838-19.


120. Jianrong Wu, Jingbo Zhang, Hongtao Zhang, Minjie Gao, Liming Liu, Xiaobei Zhan*. Recycling of cooking oil fume condensate for the production of rhamnolipids by Pseudomonas aeruginosa WB505[J]Bioprocess and Biosystems Engineering, 2020, 42: 777-784.


119. Nannan Yin (殷楠楠), Guoxing Zhu, Qiuling Luo, Jia Liu, Xiulai Chen,  Liming Liu*.Engineering of membrane phospholipid component enhances salt stress tolerance in Saccharomyces cerevisiae[J]. Biotechnology and Bioengineering, 2020, 117: 710-720.


118. Jinhui wang (王金辉), Wei Song, Jing Wu, Jia Liu, Xiulai Chen, Liming Liu*. Efficient production of phenylpropionic acids by an amino-group-transformation biocatalytic cascade[J]. Biotechnology and Bioengineering, 2020,117: 614-625.


117. Jian-Zhong Xu*, Hao-Zhe Ruan, Hai-Bo Yu, Li-Ming Liu, Weiguo Zhang. Metabolic engineering of carbohydrate metabolism systems in Corynebacterium glutamicum for improving the efficiency of L-lysine production from mixed sugar[J]. Microbial Cell Factories, 2020, 19: 39.


116. Cong Gao# (高聪), Jianshen Hou# (侯建屾), Peng Xu, Liang Guo, Xiulai Chen, Guipeng Hu, Chao Ye, Harley Edwards, Jian Chen, Wei Chen & Liming Liu*. Programmable biomolecular switches for rewiring flux in Escherichia coli[J]. Nature Communications, 2019, 10:3751-3763 .(# Authors contributed equally)


115. Cong Gao (高聪), Peng Xu, Chao Ye, Xiulai Chen, Liming Liu*. Genetic circuit-assisted smart microbial engineering[J]. Trends in Microbiology, 2019,12: 1011-1024.


114. Xiulai Chen (陈修来), Jie Zhou (周洁), Qiang Ding,Liming Liu*. Morphology engineering of Aspergillus oryzae for L-malate production[J]. Biotechnology and Bioengineering, 2019, 116: 2662-2673.


113. Yuxiang Yuan (袁宇翔), Wei Song, Jia Liu, Xiulai Chen, Qiuling Luo, Liming Liu*. Production of α-ketoisocaproate and α-keto-β-methylvalerate by engineered L-amino acid deaminase[J].ChemCatChem, 2019, 10: 2464-2472.


112. Jian-Zhong Xu*, Hai-Bo Yu, Mei Han, Li-Ming Liu, Wei-Guo Zhang. Metabolic engineering of glucose uptake systems in Corynebacterium glutamicum for improving the efficiency of L-lysine production[J]. Journal of Industrial Microbiology & Biotechnology. 2019. 46: 937-949.


111. Shihui Wang (王诗卉), Yaru Hou, Xiulai Chen, Liming Liu*. Kick-starting evolution efficiency with an autonomous evolution mutation system [J]. Metabolic Engineering, 2019, 54: 127-136.


110. Nan Xu (徐楠), Liming Liu*. Computational inference of the transcriptional regulatory network of Candida glabrata[J]. FEMS Yeast Research. 2019, 19(4).


109. Can Zhang (张灿), Wei Song, Jia Liu, Xiulai Chen, Liming Liu*Production of enantiopure (R)-or (S)-2-hydroxy-4-(methylthio)butanoic acid by multi-enzyme cascades[J]. Bioresources and Bioprocessing, 2019, 6:9-20.


108. Xiulai Chen* (陈修来), Yang Li, Tian Tong, Liming Liu. Spatial modulation and cofactor engineering of key pathway enzymes for fumarate production in Candida glabrata[J]. Biotechnology and Bioengineering, 2019, 116: 622-630.


107. Chengjin Wu (吴承晋), Jiali Zhang, Guoxing Zhu, Rui Yao, Xiulai Chen, Liming Liu*.CgHog1-mediatedCgRds2 phosphorylation alters glycerophospholipid composition to coordinate osmotic stress in Candida glabrata[J]. Applied and Environmental Microbiology, 2019, 6: e02822-18.


106. Yanli Qi (齐艳利), Hui Liu, Xiulai Chen, Liming Liu*. Engineering microbial membranes to increase stress tolerance of industrial strains[J]. Metabolic Engineering, 2019, 53:24-34.


105. Jianrong Wu*, Xiaobei Zhan, Liming Liu, Xiaole Xia*. Bioproduction, purification, and application of polysialic acid[J]. Applied Microbiology and Biotechnology, 2018, 102: 9403-9409.


104. Xiulai Chen* (陈修来), Qiuling Luo, Jia Liu,Liming Liu. Enhancement of pyruvate productivity in Candida glabrataby deleting the CgADE13 gene to improve acid tolerance[J]. Biotechnology and Bioprocess Engineering, 2018, 23: 573-579.


103. Lei Chen, ZhengqiWang, Bobo Zhang, Mengdie Ge, Huisuan Ng, Yuge Niu, Liming Liu. Production, structure and morphology of exopolysaccharides yielded by submerged fermentation of Antrodia cinnamomea[J]. Carbohydrate Polymers, 2018, 205: 271-278.


102. Yuanyuan Qian (钱园园), Jia Liu, Wei Song, Xiulai Chen, Qiuling Luo, Liming Liu*Production of β-alanine from fumaric acid using a dual-enzyme cascade[J]. ChemCatChem, 2018, 21: 4984-4991.


101. Wei Song (宋伟), Jinhui Wang, Jing Wu, Jia Liu, Xiulai Chen,Liming Liu*. Asymmetric assembly of high-value α-functionalized organic acids using a biocatalytic chiral-group-resetting process[J]. Nature Communications, 2018, 9:3818-3827.


100. Qiang Ding (丁强), Qiuling Luo, Jie Zhou, Xiulai Chen, Liming Liu*Enhancing L-malate production of Aspergillus oryzaeFMME218-37 by improving inorganic nitrogen utilization[J]. Applied Microbiology and Biotechnology, 2018, 14:1-3.


99. Weixin Zhao, Liming Liu*, Guocheng Du, Song Liu*. A multifunctional tag with the ability to benefit the expression, purification, thermostability and activity of recombinant proteins[J] Journal of Biotechnology, 2018, 283:1-10.


98. Xianzhong Chen*, Junbo Zhou, Lihua Zhang, Zhongji Pu, Liming Liu, Wei Shen, You Fan. Development of an Escherichia coli-based biocatalytic system for the efficient synthesis of N-acetyl-D-neuraminic acid[J] Metabolic Engineering, 2018, 47:374-382.


97. Hui Liu (刘晖), Lulin Kong, Yanli Qi, Xiulai Chen, Liming Liu*. Candida glabrataMed3 plays a role in altering cell size and budding index to coordinate cell growth [J]. Applied and Environmental Microbiology, 2018, 84: e00781-18.


96. Guipeng Hu (胡贵鹏), Jie Zhou, Xiulai Chen, Yuanyuan Qian, Cong Gao, Liang Guo, Peng Xu, Wei Chen, Jian Chen, Yin Li, Liming Liu*.Engineering synergetic CO2-fixing pathways for malate production[J]. Metabolic Engineering, 2018, 47: 496-504.


95. Nan Xu (徐楠), ChaoYe, Liming Liu*. Genome-scale biological models for industrial microbial systems [J]. Applied Microbiology and Biotechnology, 2018, 102:3439-3451.


94. Zhang Quan (张权),  Yao Rui,  Chen Xiulai,  Liu Liming,  Xu Shuqin,  Chen Jinghua,  Wu Jing*Enhancing fructosylated chondroitin production in Escherichia coli K4 by balancing the UDP-precursors[J]. Metabolic Engineering, 2018, 47: 314-322.


93. Xiulai Chen (陈修来),Liming Liu*. Gene circuits for dynamically regulating metabolism [J]. Trends in Biotechnology, 2018, 36: 751-754.


92. Xiulai Chen (陈修来), Guipeng Hu,Liming Liu*. Hacking algal transcription factor for lipid biosynthesis [J]. Trends in Plant Science, 2018, 23:181-184.


91. Cong Gao (高聪), Shihui Wang, Guipeng Hu, Liang Guo, Xiulai Chen, Peng Xu, Liming Liu*Engineering Escherichia coli for malate production by integrating modular pathway characterization with CRISPRi-guided multiplexed metabolic tuning[J]. Biotechnology and Bioengineering, 2018, 115:661-672.


90. Jianzhong Xu, Hankun Yang, Liming Liu, Ying-Yu Wang, Wei-Guo Zhang. Rational modification of Corynebacterium glutamicum dihydrodipicolinate reductase to switch the nucleotide-cofactor specificity for increasing l-lysine production[J]. Biotechnology and Bioengineering, 2018, 115:1764-1777.

 

89. Jianrong Yun (云建荣), Fang Duan, Liming Liu, Xiulai Chen, Jia Liu, Qiuling Luo and Jing Wu*A selective and sensitive nanosensor for fluorescent detection of specific IgEs to purified allergens in human serum[J]. RSC Advances, 2018, 8:3547-3555.


88.Xiaobao Lin(林小宝), Yanli Qi, Dongni Yan, Hui Liu, Xiulai Chen, Liming Liu*. CgMED3 changes membrane sterol composition to help Candida glabrata tolerate low pH stress[J]. Applied and Environmental Microbiology, 2017, 83: e00972-17.


87. Wen Qin (秦雯), Chengjin Wu, Wei Song, Xiulai Chen, Jia Liu, Qiuling Luo,Liming Liu*.A novel high-yield process of phospholipase D-mediated phosphatidylserine production with cyclopentyl methyl ether[J]. Process Biochemistry, 2017, 66:146-149.


86. Li Wang(王立), Chenchen Liang, Jing Wu*., Liming Liu, Keith E. J. Tyo. Increased processivity, misincorporation, and nucleotide incorporation efficiency in Sulfolobus solfataricus Dpo4 thumb domain mutants[J]. Applied and Environmental Microbiology, 2017, 83:e01013-17.


85. Bin Yang (杨彬), Hongjiang Wang, Wei Song, Xiulai Chen, Jia Liu, Qiuling Luo, Liming Liu*Engineering of the conformational dynamics of lipase to increase enantioselectivity[J]. ACS Catalysis, 2017, 7:7593-7599.


84. Yanli Qi (齐艳利), Hui Liu, Jiayin Yu, Xiulai Chen, Liming Liu*. Med15B regulates acid stress response and tolerance in Candida glabrataby altering membrane lipid composition[J]. Applied and Environmental Microbiology, 2017, 83: e01128-17.


83. Xiaobao Lin# (林小宝), Yanli Qi# (齐艳利), Dongni Yan, Hui Liu, Xiulai Chen, Liming Liu*. CgMED3 changes membrane sterol composition to help Candida glabratatolerate low pH stress[J]. Applied and Environmental Microbiology, 2017, 83: e00972-17. (# Authors contributed equally)


82. Xiulai Chen (陈修来), Cong Gao, Liang Guo, Guipeng Hu, Qiuling Luo, Jia Liu, Jian Chen, Jens Nielsen, Liming Liu*. DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals[J]. Chemical Reviews, 2018, 118: 64-72.


81. Nan Xu (徐楠), Chao Ye, Xiulai Chen, Jia Liu, Liming Liu*. Genome-scale metabolic modelling common cofactors metabolism in microorganisms[J]. Journal of Biotechnology, 2017, 251:1-13.


80. Anran Sun (孙安然), Wei Song, Weihua Qiao, Xiulai Chen, Jia Liu, Qiuling Luo, Liming Liu*. Efficient agmatine production using an arginine decarboxylase with substrate-specific activity[J]. Journal of Chemical Technology and Biotechnology, 2017, 92:2383-2391.


79. Xiulai Chen (陈修来), Yuancai Wang, Xiaoxiang Dong, Guipeng Hu, Liming Liu*. Engineering rTCA pathway and C4-dicarboxylate transporter for L-malic acid production[J]. Applied Microbiology and Biotechnology, 2017, 101: 4041-4052.


78.Ye Chao (叶超), Xu Nan, Dong Chuan, Ye Yuannong, Zou Xuan, Chen Xiulai, Guo Fengbiao, Liu Liming*. IMGMD: A platform for the integration and standardization of in silico microbial genome-scale metabolic models[J]. Scientific Reports, 2017, 7: 727.


77. Jing Wu (吴静), Hongjiang Wang, Bin Yang, Wei Song, Chenchen Liang,  Liming Liu*Efficient production of (R)-3-TBDMSO glutaric acid methyl monoester by manipulating the substrate pocket of Pseudozyma antarctica lipase B[J]RSC Advances, 2017, 7: 38264-38272.


76. Xiulai Chen (陈修来), Wei Song, Cong Gao, Wen Qin, Qiuling Luo, Jia Liu,Liming Liu*. Fumarate production by Torulopsis glabrata: Engineering the heterologous fumarase and the acid tolerance[J]. PLoS One, 2016, 11:e0164141.


75. Xiaoxiang Dong (董晓翔), Xiulai Chen, Yuanyuan Qian, Yuancai Wang, Li Wang, Weihua Qiao,Liming Liu*. Metabolic engineering of Escherichia coli W3110 to produce L-malate[J]. Biotechnology and Bioengineering, 2017, 114:656-664.


74. Dongni Yan (闫冬妮), Xiaobao Lin, Yanli Qi, Hui Liu, Xiulai Chen, Liming Liu*, Jian Chen. Crz1p regulates pH homeostasis in Candida glabrataby altering membrane lipid composition[J]. Applied and Environmental Microbiology, 2016, 82:6920-6929.


73. Xu Nan (徐楠), Ye Chao, Chen Xiulai, Liu Jia, Liu Liming*, Chen Jian. Genome Sequencing of the Pyruvate-producing Strain Candida glabrata CCTCC M202019 and Genomic Comparison with Strain CBS138Scientific Reports. 2016, 6: 34893.


72. Xiangchen Fan (樊祥臣), Lele Chen, Liming Liu*. Enhancement of alpha-ketoglutaric acid production from l-glutamic acid by high-cell-density cultivation[J]. Journal of Molecular Catalysis B: Enzymatic, 2016,126:10-17.


71. Chao Ye (叶超), Weihua Qiao, Xiaobin Yu, Xiaojun Ji, He Huang, Jackie L. Collier, Liming Liu*. Reconstruction and analysis of the genome-scale metabolic model of Schizochytrium limacinum SR21 for docosahexaenoic acid production[J]. BMC Genomics, 2015, 16:799.


70. Jie Mei (梅婕), Nan Xu, Chao Ye, Liming Liu*, Jianrong Wu. Reconstruction and analysis of a genome-scale metabolic network of Corynebacterium glutamicum S9114[J]. Gene, 2015, 575:615-622.


69. Xiulai Chen (陈修来), Pan Zhu, Liming Liu*. Modular optimization of multi-gene pathways for fumarate production[J]. Metabolic Engineering, 2016, 33:76-85.


68. Hongjiang Wang (王鸿江), Zebiao Li , Xiaoxia Yu, Ruidong Chen, Xiulai Chen, Liming Liu*. Green synthesis of (R)-3-TBDMSO glutaric acid methyl monoester using Novozym 435 in non-aqueous media[J]. RSC Advances, 2015, 5:75160-75166.


67. Xia Sun (孙霞), Wei Song, Liming Liu*.Enzymaticproduction of agmatine by recombinant arginene decarboxylase[J].Journal of Molecular Catalysis B: Enzymatic,2015, 121:1-8.


66. Wei Song (宋伟), Xia Sun, Xiulai Chen, Dongxu Liu, Liming Liu*. Enzymatic production of L-citrulline by hydrolysis of the guanidinium group of L-arginine with recombinant Arginine Deiminase[J]. Journal of Biotechnology, 2015, 208:37-43.

 

65. Shubo Li (李树波), Liming Liu*, Jian Chen*. Mitochondrial fusion and fission are involved in stress tolerance of Candida glabrata [J]. Bioresources and Bioprocessing, 2015, 2:12-20.


64. Xiulai Chen (陈修来), Xiaoxiang Dong, Yuancai Wang, Zihao Zhao, Liming Liu*Mitochondrial engineering of the TCA cycle for fumarate production[J]. Metabolic Engineering, 2015,31:62-73.


63. Chao Ye (叶超), Nan Xu, Haiqin Chen, Yong Q Chen, Wei Chen, Liming Liu*. Reconstruction and analysis of a genome-scale metabolic model of the oleaginous fungus Mortierella alpina [J]. BMC Systems Biology, 2015, 9:1-11.


62. Nan Xu (徐楠), Jie Liu, Lianzhong Ai, Liming Liu*. Reconstruction and analysis of the genome-scale metabolic model of Lactobacillus casei LC2W [J]. Gene, 2015, 554:140-147.


61. Shubo Li (李树波), Liming Liu*, Jian Chen*.Compartmentalizing metabolic pathway in candida glabrata for acetoin production[J]. Metabolic Engineering, 2015, 28:1-7.


60. Wei Song (宋伟), Panqing Niu, Xiulai Chen, Liming Liu*Enzymatic production of l-ornithine from l-arginine with recombinant thermophilic arginase[J]. Journal of Molecular Catalysis B: Enzymatic, 2014, 110:1-7.


59. Xiulai Chen (陈修来), Jing Wu, Wei Song, Limei Zhang, Hongjiang Wang, Liming Liu*.Fumaric acid production by Torulopsis glabrata: Engineering the urea cycle and the purine nucleotide cycle[J]. Biotechnology and Bioengineering, 2015, 112:156-167.


58. Xiulai Chen (陈修来), Shubo Li, Liming Liu*Engineering redox balance through cofactor systems[J]. Trends in Biotechnology, 2014, 32: 337-343.


57. Chao Ye (叶超), Wei Zou, Nan Xu, Liming Liu*.Metabolic model reconstruction and analysis of an artificial microbial ecosystem for vitamin C[J]. Journal of Biotechnology. 2014, 183:61–67.


56. Shubo Li (李树波), Nan Xu, Liming Liu*, Jian Chen. Engineering of carboligase activity reaction in Candida glabrata for acetoin production [J]. Metabolic Engineering, 2014, 22:32-39.


55. Shubo Li (李树波), Xiang Gao, Nan Xu, Liming Liu*, Jian Chen*. Enhancement of acetoin production in Candida glabrata by in silico-aided metabolic engineering[J]. Microbial Cell Factories, 2014, 13: 55.


54. Shubo Li (李树波), Xiulai Chen, Liming Liu*, Jian Chen. Pyruvate production in Candida glabrata: manipulation and optimization of physiological function[J]. Critical Reviews in Biotechnology, 2013, 30:1-10.


53. Xiaoxia Yu (俞晓霞), Hongjiang Wang, Liming Liu*. Two non-exclusive strategies employed to protect Torulopsis glabrata against hyperosmotic stress[J]. Applied Microbiology and Biotechnology, 2014, 98:3099-3110.


52. Qian Gao (高倩), Jie Liu, Liming Liu*. Relationship between morphology and itaconic acid production by Aspergillus terreus[J]. Journal of Microbiology and Biotechnology, 2014, 24:168-176.


51. Xiang Gao (高翔), Nan Xu, Shubo Li, Liming Liu*. Metabolic Engineering of Candida glabrata for Diacetyl Production[J]. Plos One, 2014, 9:e89854.


50. Panqing Niu (牛盼清), Xiaoxiang Dong, Yuancai Wang, Liming Liu*. Enzymatic production of α-ketoglutaric acid from L-glutamic acid via L-glutamate oxidase[J]. Journal of Biotechnology, 2014, 179:56-62.


49. Jia Liu (刘佳), Aihua Yang, Jie Liu, Xiaofan Ding, Liming Liu*, Zhongping Shi. KfoE encodes a fructosyltransferase involved in capsular polysaccharide biosynthesis in Escherichia coli K4[J]. Biotechnology Letters, 2014, 36:1469-1477.


48. Songxin Yang (杨松鑫), Xiulai Chen, Nan Xu, Liming Liu*, Jian Chen. Urea enhances cell growth and pyruvate production in Torulopsis glabrata. [J] Biotechnology Progress, 2014, 30: 19-27.


47. Shicun Fan(樊世存), Zhang ZY, Zou W, Huang Z, Liu J, Liming Liu*. Development of a minimal chemically defined medium for Ketogulonicigenium vulgare WSH001 based on its genome-scale metabolic model.[J]. Journal of Biotechnology, 2014, 169: 15-22.


46. Agren R#, Liming Liu#, Shoaie S, Vongsangnak W, Nookaew I, Nielsen J*. The RAVEN toolbox and its use for generating a genome-scale metabolic model for Penicillium chrysogenum. [J].PLoS Computational Biology, 2013, 9: e1002980. (# Authors contributed equally)

 

45.Wu QL(吴秋林), Yang AH, Zou W, Duan ZY, Liu J, Chen J, Liu L-M*. Transcriptional engineering of Escherichia coli K4 for fructosylated chondroitin production. [J].Biotechnology Progress, 2013, 29: 1140-1149.


44.Chen XL(陈修来), Xu GQ, Xu N, Zou W, Zhu P, Liu L-M*, Chen J. Metabolic engineering of Torulopsis glabrata for malate production. [J].Metabolic Engineering, 2013, 19: 10-16.


43.Huang Z(黄政), Zou W, Liu J, Liu L-M*. Glutathione enhances 2-keto-L-gulonic acid production based on Ketogulonicigenium vulgare model iWZ663.[J]. Journal of Biotechnology, 2013, 164: 454-460.


42.Liu J(刘杰), Gao Q, Xu N, Liu L-M*. Genome-scale reconstruction and in silico analysis of Aspergillus terreus metabolism. [J]. Molecular Biosystems, 2013, 9: 1939-1948.


41.Xu GQ(徐国强), Chen XL, Liu L-M*, Jiang LH. Fumaric acid production in Saccharomyces cerevisiae by simultaneous use of oxidative and reductive routes. [J]. Bioresource Technology, 2013, 148: 91-96.


40.Xu N(徐楠), Liu L-M*, Zou W, Liu J, Hua Q, Chen J. Reconstruction and analysis of the genome-scale metabolic network of Candida glabrata. [J]. Molecular Biosystems, 2013, 9: 205-216.


39.Zou W(邹伟), Liu L-M*, Chen J. Structure, mechanism and regulation of an artificial microbial ecosystem for vitamin C production. [J].Critical Reviews in Microbiology, 2013, 39: 247-255.


38.Zou W(邹伟), Zhou MD, Liu L-M*, Chen J. Reconstruction and analysis of the industrial strain Bacillus megaterium WSH002 genome-scale in silico metabolic model. [J].Journal of Biotechnology, 2013, 164: 503-509.


37.Zhang YJ(张燕婕), Li SB, Liu L-M, Wu J*. Acetoin production enhanced by manipulating carbon flux in a newly isolated Bacillus amyloliquefaciens. [J].Bioresource Technology, 2013, 130: 256-260.


36.Xu GQ(徐国强), Zou W, Chen XL, Xu N, Liu L-M*, Chen J*. Fumaric acid production in Saccharomyces cerevisiae by in silico aided metabolic engineering. [J] PLoS One, 2012, 7: e52086.


35.Liu T(刘婷), Zou W, Liu L-M*, Chen J. A constraint-based model of Scheffersomyces stipitis for improved ethanol production. [J] Biotechnology for Biofuels, 2012, 5: 72.

 

34.Xu GQ(徐国强), Hua Q, Duan NJ, Liu L-M*, Chen J. Regulation of thiamine synthesis in Saccharomyces cerevisiae for improved pyruvate production. [J] Yeast, 2012, 29: 209-217.

 

33.Zou W(邹伟), Liu L-M*, Zhang J, Yang HR, Zhou MD, Hua Q, Chen J. Reconstruction and analysis of a genome-scale metabolic model of the vitamin C producing industrial strain Ketogulonicigenium vulgare WSH-001.[J] Journal of Biotechnology, 2012, 161: 42-48.

 

32.Xu GQ(徐国强), Liu L-M*, Chen J*. Reconstruction of cytosolic fumaric acid biosynthetic pathways in Saccharomyces cerevisiae. [J] Microbial Cell Factories, 2012, 11: 24.


31. Jing Zhang (张静), Jie Liu, Liu Liming*, Jian Chen*. Development of chemically defined media supporting high cell density growth of Ketogulonicigenium vulgare and Bacillus megaterium[J]. Bioresource Technology, 2011, 102:4807-4814.


30. Sha Xu (徐沙), Jingwen Zhou, Liming Liu*, Jian Chen*. Arginine: a novel compatible solute to protect Candida glabrata against hyperosmotic stress[J]. Process Biochemistry, 2011, 44:1230-1235.


29. Yi Qin (秦义), Clayton H. Johnson, Liming Liu*, Jian Chen. Introduction of heterogeneous NADH reoxidation pathways into Torulopsis glabrata significantly increases pyruvate production efficiency[J]. Korean Journal of Chemical Engineering, 2011, 28:1078-1084.


28. Jingwen Zhou (周景文), Liming Liu*, Jian Chen*. Improved ATP supply enhances acid tolerance of Candida glabrata during pyruvic acid production[J]. Journal of Applied Microbiology, 2011, 110:44-53.


27. Liming Liu (刘立明)*, Kejie Chen, Jian Chen. Gelatin enhances 2-keto-L-gulonic acid production based on Ketogulonigenium vulgare genome annotation[J]. Journal of Biotechnology, 2011, 156:182-187.


26. Liming Liu (刘立明), Yang Li, Jing Zhang, Min Li, Wei Zou, Lei Wang and Jian Chen*. Complete Genome Sequence of the industrial strain Bacillus megaterium WSH-002[J]. Journal of Bacteriology, 2011, 193:6389- 6390.


25. Liming Liu (刘立明), Yang Li, Jing Zhang, Zhemin Zhou, Jie Liu, Xiaomin Li, Jingwen Zhou, Guocheng Du, Lei Wang, Jian Chen*. Complete genome sequence of the industrial strain Ketogulonicigenium vulgare WSH-001[J]. Journal of Bacteriology, 2011, 193: 6108-6109.


24. Feng Wang*, Zhenggang Cui, Liming Liu*. Comparison of covalent immobilization of amylase on polystyrene pellets with pentaethylenehexamine and pentaethylene glycol spacers[J]. Bioresource Technology, 2011, 102:9374-9379


23. Sha Xu (徐沙), Liming Liu, Du Guocheng, Chen Jian*. Enhancement of pyruvate production by Torulopsis glabrata: Proline as osmotic-protector[J]. Biotechnology and Bioprocess Engineering, 2010, 15:285-292.


22. Sha Xu (徐沙), Liming Liu*, Chen Jian*.Water-forming NADH oxidase protects Torulopsis glabrata against hyperosmotic stress[J]. Yeast, 2010, 27:207-216.


21. Jingwen Zhou (周景文), Liming Liu*, Jian Chen*. Mitochondrial DNA heteroplasmy in Candida glabrata after mitochondrial transformation[J]. Eukaryotic Cell, 2010, 9: 806-814.


20. Jing Zhang (张静), Jie Liu, Zhongping Shi, Liming Liu*, Jian Chen*. Manipulation of B. megaterium growth for efficient 2-KLG production by K. vulgar[J]. Process Biochemistry, 2010, 45:602-606.


19. Liming Liu (刘立明), Rasmus Agren, Sergio Bordel, Jens Nielsen*. Use of genome-scale metabolic models for understanding microbial physiology[J]. FEBS Letters, 2010, 584:2556-2564.


18. Jingwen Zhou (周景文), Haiyan Zhou*, Guocheng Du, Liming Liu, Jian Chen. Screening of a thiamin auxotrophic yeast for α-ketoglutaric acid overproduction[J]. Letters in Applied Microbiology, 2010, 51:264-71.


17. Jingwen Zhou (周景文), Liming Liu*, Jian Chen*. Method to purify mitochondrial DNA directly from yeast total DNA[J]. Plasmid. 2010, 64:196-199.


16. Yi Qin (秦义), Liming Liu*,Changhao Li, Sha Xu, Jian Chen*. Accelerating glycolytic flux of Torulopsis glabrata CCTCC M202019 at high oxidoreduction potential created by potassium ferricyanide[J]. Biotechnology Progress, 2010, 26:1551-1557.


15. Jingwen Zhou (周景文), Liming Liu*, Zhongping Shi, Guocheng Du, Jian Chen*. ATP in Current Biotechnology: Regulation, Application and Perspectives[J]. Biotechnology Advance, 2009, 27:94-101.


14. Jingwen Zhou (周景文), Liming Liu*, Zhongping Shi, Guocheng Du, Jian Chen*. A reusable method for construction of non-marker large fragment deletion yeast auxotroph strains: a practice in Torulopsis glabrata[J]. Journal of Microbiological Methods, 2009, 76:70-74.


13. Dandan Zhang (张旦旦), Nan Liang,Zhongping Shi, Liming Liu*, Jian Chen*, Guocheng Du. Enhancement of α-ketoglutarate production in Torulopsis glabrata: Redistribution of carbon flux from pyruvate to α-ketoglutarate[J]. Biotechnology and Bioprocess Engineering,2009, 14:134-139.


12. Jingwen Zhou (周景文), Luxi Huang, Liming Liu, Jian Chen*. Enhancement of pyruvate productivity by inducible expression of a F0F1-ATPase inhibitor INH1 in Torulopsis glabrata CCTCC M202019.[J] Journal of Biotechnology, 2009, 144:120-126.


11. Liming Liu (刘立明), Miao Wang, Guocheng Du*, Jian Chen. Enhanced hyaluronic acid production of Streptococcus zooepidemicus by an intermittent alkaline-stress strategy. [J] Letters in Applied Microbiology, 2008, 46: 383-388.


10. Liming Liu (刘立明), Qinglong Xu, Yin Li, Zhongpin Shi, Yang Zhu, Gucheng Du, Jian Chen*. Enhancement of pyruvate production by osmotic-tolerant mutant of Torulopsis glabrata.[J] Biotechnology and Bioengineering, 2007, 97: 825-832.


9. Guocheng Du (堵国成), Liu Liming, Zhaoxia Song, Zhaozhe Hua, Yang Zhu, Jian Chen. Screening of PVA-degrading enzyme producing microorganism Janthinobacteriumsp. and its application in cotton fabric desizing.[J] Biotechnology Journal, 2007, 2:752-758.


8. Liming Liu (刘立明), Yin Li, Yang Zhu, Guocheng Du, Jian Chen*. Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level.[J] Metabolic Engineering, 2007, 9: 21-29.


7. Liming Liu (刘立明), Yin Li, Jian Chen*. Enhancement of pyruvate productivity in Torulopsis glabrata: increase of NAD+ availability. [J] Journal of Biotechnology, 2006, 26: 173-185.


6. Huang H-J,Liming Liu, Yin Li, Guocheng Du, Jian Chen*. Redirecting carbon flux in Torulopsis glabratafrom pyruvate toa-ketoglutaric acid by changing metabolic co-factors and glucose level. [J] Biotechnology Letter, 2006, 28: 95-98.


5. Liming Liu (刘立明), Yin Li, Guocheng Du, Jian Chen*. Increasing glycolytic flux in Torulopsis glabrataby redirecting ATP production from oxidative phosphorylation to substrate-level phosphorylation. [J] Journal of Applied Microbiology, 2006, 100: 1043-1053.


4. Liming Liu (刘立明), Yin Li, Huazhong Li,  Jian Chen*. Significant increase of glycolytic flux in Torulopsis glabrata by inhibition of oxidative phosphorylation.[J] FEMS Yeast Research, 2006, 6: 1117-1129.


3. Liming Liu (刘立明), Yin Li, Jian Chen*. Redirection of NADH regeneration pathway in Torulopsis glabrataleads to an enhanced pyruvate production. [J] Applied Microbiology Biotechnology,2006, 72: 377-385.


2. Liming Liu (刘立明), Guocheng Du, Yin Li, Huazhong Li, Jian Chen*.Enhancement of pyruvate production by Torulopsis glabrata through supplement of oxaloacetate as carbon source. [J] Biotechnology and Bioprocess Engineering, 2005, 10: 136-141


1. Liming Liu (刘立明), Yin Li, Huazhong Li, Jian Chen*. Manipulating the pyruvate dehydrogenase bypass of a multi-vitamin auxotrophic yeast Torulopsis glabrata enhanced pyruvate production.[J] Letters in Applied Microbiology, 2004, 39: 199-206.